Outdoor & Yard / Compounds / Azoxystrobin

Azoxystrobin in the yard and garden

Moderate risk for your yard

Not medical, veterinary, or professional safety advice, and not a substitute for a qualified professional — consult one. Full disclaimer →

Safety profile for Azoxystrobin relevant to people, pets, and pollinators.

What is azoxystrobin?

The IUPAC name is methyl (E)-2-(2-(6-(2-cyanophenoxy)pyrimidin-4-yl)oxyacetyl)benzoate.

Also known as: methyl (E)-2-(2-(6-(2-cyanophenoxy)pyrimidin-4-yl)oxyacetyl)benzoate, Amistar, Bankit, Heritage.

IUPAC name
methyl (E)-2-(2-(6-(2-cyanophenoxy)pyrimidin-4-yl)oxyacetyl)benzoate
CAS number
131860-33-8
Molecular formula
C22H17N3O5
Molecular weight
403.39 g/mol
SMILES
COC=C(C1=CC=CC=C1OC2=NC=NC(=C2)OC3=CC=CC=C3C#N)C(=O)OC
PubChem CID
3034285

Risk for people, pets,

Moderate risk

Regulatory consensus

2 regulatory and scientific bodies have classified Azoxystrobin. The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA—Strobilurin fungicide; general use pesticideapproved
IARC—No classificationinsufficient evidence

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where your yard encounter azoxystrobin

  • agricultural fungicide (cereals, fruits, vegetables)
  • turf fungicide
  • crop residues

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Azoxystrobin:

  • Trifloxystrobin (same QoI class, lower aquatic toxicity)
    Trade-offs: Same mode of action (FRAC Group 11) — cross-resistance. Lower aquatic toxicity profile.
    Relative cost: Similar
  • Copper hydroxide (inorganic fungicide)
    Trade-offs: Copper accumulation in soil. Lower efficacy for some diseases. Contact-only (no systemic activity).
    Relative cost: 0.5×

Frequently asked questions

What products contain azoxystrobin?

Azoxystrobin appears in: agricultural fungicide (cereals, fruits, vegetables); turf fungicide; crop residues.

Why do regulators disagree about azoxystrobin?

Azoxystrobin has been classified by 2 agencies including EPA, IARC, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Azoxystrobin in the outdoor app

Look up products containing azoxystrobin, compare to alternatives, and explore the full data record.

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Sources (1)
  1. ATSDR Toxicological Profile — CAS 131860-33-8 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →