Outdoor & Yard / Compounds / Metribuzin

Metribuzin in the yard and garden

Moderate risk for your yard

Safety profile for Metribuzin relevant to people, pets, and pollinators.

What is metribuzin?

The IUPAC name is 4-amino-6-methyl-4H-1,2,4-triazin-5-one 3-tert-butyl.

Also known as: 4-amino-6-methyl-4H-1,2,4-triazin-5-one 3-tert-butyl, Lexone, Sencor, Metribuzine.

IUPAC name
4-amino-6-methyl-4H-1,2,4-triazin-5-one 3-tert-butyl
CAS number
21087-64-9
Molecular formula
C8H14N4OS
Molecular weight
214.28 g/mol
SMILES
CC(C)(C)C1=NN=C(N(C1=O)N)SC
PubChem CID
30479

Risk for people, pets,

Moderate risk

Regulatory consensus

2 regulatory and scientific bodies have classified Metribuzin. The classifications differ — that's the data.

AgencyYearClassificationNotes
EPA
IARC

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where your yard encounter metribuzin

  • agricultural herbicide (potatoes, soybeans)
  • crop residues
  • groundwater

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Metribuzin:

  • S-metolachlor + metribuzin reduced-rate program
    Trade-offs: Reduced (not eliminated) metribuzin use. Better groundwater profile than full-rate.
    Relative cost: Similar
  • Cover crop suppression + mechanical cultivation
    Trade-offs: Labor-intensive. Less consistent than chemical control. Requires timing expertise.
    Relative cost: Variable; potential savings on herbicide

Frequently asked questions

What products contain metribuzin?

Metribuzin appears in: agricultural herbicide (potatoes, soybeans); crop residues; groundwater.

See Metribuzin in the outdoor app

Look up products containing metribuzin, compare to alternatives, and explore the full data record.

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Sources (1)

  1. ATSDR Toxicological Profile — CAS 21087-64-9 — reference

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →