Outdoor & Yard / Compounds / Nitrogen dioxide (NO₂)

Nitrogen dioxide (NO₂) in the yard and garden

Moderate risk for your yard

NO₂ is a WHO criteria air pollutant and a key indicator of combustion-related outdoor air pollution (vehicle exhaust, power plants). IARC has not classified NO₂ alone as a carcinogen; the cancer risk from traffic-related air pollution is attributed to the mixture including PM2.5 and benzene rather than NO₂ specifically. Primary non-cancer hazard: inflammatory airway injury (NO₂ reacts with airway lining fluid to generate nitrous/nitric acid and free radicals). WHO 24-hour guideline: 25 μg/m³; US EPA 1-hour NAAQS: 100 ppb. Indoor sources: gas stoves, unvented combustion appliances, cigarette smoke. Occupational exposure (welding, firefighting) can cause pulmonary edema at high acute doses (silo filler's disease).

What is nitrogen dioxide (no₂)?

Also known as: Nitrogen peroxide, Dioxide, Nitrogen, Peroxide, Nitrogen, Nitrogen oxide (NO2).

CAS number
10102-44-0
Molecular formula
NO2
Molecular weight
46.006 g/mol
SMILES
N(=O)[O]
PubChem CID
3032552

Risk for people, pets,

Moderate risk

NO₂ is a WHO criteria air pollutant and a key indicator of combustion-related outdoor air pollution (vehicle exhaust, power plants). IARC has not classified NO₂ alone as a carcinogen; the cancer risk from traffic-related air pollution is attributed to the mixture including PM2.5 and benzene rather than NO₂ specifically. Primary non-cancer hazard: inflammatory airway injury (NO₂ reacts with airway lining fluid to generate nitrous/nitric acid and free radicals). WHO 24-hour guideline: 25 μg/m³; US EPA 1-hour NAAQS: 100 ppb. Indoor sources: gas stoves, unvented combustion appliances, cigarette smoke. Occupational exposure (welding, firefighting) can cause pulmonary edema at high acute doses (silo filler's disease).

Regulatory consensus

12 regulatory and scientific bodies have classified Nitrogen dioxide (NO₂). The classifications differ — that's the data.

AgencyYearClassificationNotes
WHOcriteria air pollutantkey indicator of combustion-related outdoor air pollution
IARCnot classified as a carcinogen (NO₂ alone)cancer risk from traffic-related air pollution attributed to mixture including PM2.5 and benzene rather than NO₂ specifically
EPA CTX / GenetoxGenotoxicity: positive (Ames: positive, 4 positive / 0 negative reports)
EPA CTX / GenetoxGenotoxicity: positive (Ames: positive, 4 positive / 0 negative reports)
EPA CTX / Skin-EyeSkin Irritation: Skin Corr. 1B (score: very high)
EPA CTX / Skin-EyeEye Irritation: Serious eye damage/eye irritation - Category 1 (score: very high)
EPA CTX / Skin-EyeSkin Irritation: Skin corrosion/irritation - Category 2 (score: high)
EPA CTX / Skin-EyeEye Irritation: Category 2 (score: high)
EPA CTX / Skin-EyeEye Irritation: Eye Dam. 1 (score: very high)
EPA CTX / Skin-EyeSkin Irritation: Skin Corr. 1B (score: very high)
EPA CTX / Skin-EyeEye Irritation: Category 8.3A (Category 1) (score: very high)
EPA CTX / Skin-EyeSkin Irritation: Category 8.2A (Category 1A) (score: very high)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where your yard encounter nitrogen dioxide (no₂)

  • Outdoor AirVehicle exhaust, Industrial emissions, Power plant discharge
  • Indoor AirCombustion byproducts, Office buildings, Parking garages

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Nitrogen dioxide (NO₂):

  • Safer process chemistry; Green chemistry alternatives; Exposure controls
    Trade-offs: Requires R&D investment to redesign synthesis routes; may reduce yield or throughput initially; long-term benefits include reduced waste treatment costs, regulatory compliance, and worker safety; 12 Principles of Green Chemistry framework available.
    Relative cost: 1.2-2×

Frequently asked questions

Is nitrogen dioxide (no₂) safe for your yard?

NO₂ is a WHO criteria air pollutant and a key indicator of combustion-related outdoor air pollution (vehicle exhaust, power plants). IARC has not classified NO₂ alone as a carcinogen; the cancer risk from traffic-related air pollution is attributed to the mixture including PM2.5 and benzene rather than NO₂ specifically. Primary non-cancer hazard: inflammatory airway injury (NO₂ reacts with airway lining fluid to generate nitrous/nitric acid and free radicals). WHO 24-hour guideline: 25 μg/m³; US EPA 1-hour NAAQS: 100 ppb. Indoor sources: gas stoves, unvented combustion appliances, cigarette smoke. Occupational exposure (welding, firefighting) can cause pulmonary edema at high acute doses (silo filler's disease).

What products contain nitrogen dioxide (no₂)?

Nitrogen dioxide (NO₂) appears in: Vehicle exhaust (Outdoor air); Industrial emissions (Outdoor air); Combustion byproducts (Indoor air); Office buildings (Indoor air).

Why do regulators disagree about nitrogen dioxide (no₂)?

Nitrogen dioxide (NO₂) has been classified by 12 agencies including WHO, IARC, EPA CTX / Genetox, EPA CTX / Genetox, EPA CTX / Skin-Eye, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Nitrogen dioxide (NO₂) in the outdoor app

Look up products containing nitrogen dioxide (no₂), compare to alternatives, and explore the full data record.

Open in outdoor View raw API data

Sources (3)

  1. US EPA National Ambient Air Quality Standards for Nitrogen Dioxide (2010) — regulatory
  2. WHO Air Quality Guidelines for Nitrogen Dioxide (Global Update 2021) (2021) — regulatory
  3. ATSDR Toxicological Profile for Nitrogen Oxides (2002) — report

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →